Indoles and derivatives
- (1)
- (1)
- (2)
- (389)
- (4)
- (2)
- (2)
- (22)
- (28)
- (2)
- (29)
- (1)
- (30)
- (1)
- (1)
- (54)
- (114)
- (4)
- (13)
- (2)
- (10)
- (1)
- (73)
- (1)
- (279)
- (2)
- (1)
- (6)
- (12)
- (1)
- (32)
- (1)
- (12)
- (2)
- (6)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (2)
- (2)
- (1)
- (5)
- (4)
- (3)
- (2)
- (23)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (3)
- (4)
- (2)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (7)
- (5)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (13)
- (3)
- (4)
- (7)
- (1)
- (10)
- (1)
- (7)
- (1)
- (11)
- (5)
- (4)
- (5)
- (1)
- (2)
- (11)
- (1)
- (1)
- (1)
- (2)
- (1)
- (2)
- (2)
- (4)
- (1)
- (2)
- (2)
- (6)
- (2)
- (2)
- (4)
- (21)
- (16)
- (2)
- (2)
- (4)
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (3)
- (1)
- (1)
- (1)
- (1)
- (1)
- (7)
- (2)
- (1)
- (1)
- (2)
- (2)
- (1)
- (1)
- (2)
- (1)
- (1)
- (13)
- (2)
- (1)
- (2)
- (2)
- (1)
- (6)
- (2)
- (1)
- (1)
- (1)
- (1)
- (7)
- (3)
- (1)
- (2)
- (4)
- (8)
- (1)
- (1)
- (7)
- (1)
- (1)
- (4)
- (5)
- (2)
- (2)
- (1)
- (1)
- (2)
- (3)
- (1)
- (1)
- (1)
- (2)
- (2)
- (1)
- (2)
- (5)
- (4)
- (12)
- (1)
- (5)
- (2)
- (6)
- (1)
- (2)
- (2)
- (1)
- (1)
- (7)
- (2)
- (2)
- (2)
- (9)
- (7)
- (2)
- (3)
- (2)
- (9)
- (2)
- (1)
- (2)
- (3)
- (1)
- (1)
- (1)
- (1)
- (3)
- (1)
- (2)
- (2)
- (2)
- (7)
- (1)
- (4)
- (2)
- (2)
- (2)
- (3)
- (1)
- (2)
- (4)
- (1)
- (1)
- (2)
- (5)
- (2)
- (1)
- (2)
- (4)
- (4)
- (2)
- (3)
- (5)
- (1)
- (1)
- (2)
- (1)
- (6)
- (3)
- (8)
- (1)
- (2)
- (1)
- (1)
- (2)
- (2)
- (1)
- (2)
- (2)
- (1)
- (1)
- (3)
- (2)
- (2)
- (1)
- (2)
- (1)
- (2)
- (2)
- (1)
- (1)
- (1)
- (4)
- (5)
- (1)
- (2)
- (7)
- (5)
- (1)
- (2)
- (2)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (4)
- (2)
- (2)
- (3)
- (2)
- (3)
- (2)
- (2)
- (1)
- (2)
- (5)
- (1)
- (2)
- (2)
- (2)
- (2)
- (3)
- (1)
- (1)
- (4)
- (2)
- (1)
- (1)
- (2)
- (1)
- (1)
- (2)
- (2)
- (2)
- (8)
- (7)
- (4)
- (2)
- (1)
- (2)
- (2)
- (2)
- (2)
- (5)
- (2)
- (2)
- (3)
- (2)
- (2)
- (2)
- (2)
- (2)
- (3)
- (3)
- (3)
- (3)
- (2)
- (1)
- (2)
- (1)
- (1)
- (1)
- (4)
- (4)
- (1)
- (2)
- (9)
- (7)
- (2)
- (1)
- (1)
- (7)
- (2)
- (1)
- (1)
- (2)
- (4)
- (4)
- (2)
- (2)
- (1)
- (4)
- (5)
- (6)
- (1)
- (1)
- (2)
- (2)
- (1)
- (1)
- (8)
- (2)
- (2)
- (1)
- (1)
- (2)
- (2)
- (17)
- (2)
- (2)
- (2)
- (2)
- (2)
- (1)
- (1)
- (4)
- (4)
- (5)
- (2)
- (1)
- (4)
- (1)
- (1)
- (1)
- (1)
- (4)
- (3)
- (1)
- (1)
- (4)
- (8)
- (2)
- (2)
- (6)
- (2)
- (2)
- (1)
- (1)
- (2)
- (2)
- (2)
- (2)
- (1)
- (2)
- (1)
- (2)
- (5)
- (4)
- (2)
- (2)
- (1)
- (2)
- (2)
- (1)
- (2)
- (3)
- (3)
- (2)
- (4)
- (4)
- (2)
- (2)
- (1)
- (2)
- (5)
- (1)
- (2)
- (2)
- (2)
- (1)
- (2)
- (6)
- (2)
- (2)
- (2)
- (1)
- (2)
- (4)
- (2)
- (2)
- (4)
- (1)
- (1)
- (1)
- (2)
- (1)
- (2)
- (4)
- (2)
- (2)
- (3)
- (2)
- (1)
- (2)
- (2)
- (2)
- (2)
- (1)
- (1)
- (2)
- (1)
- (2)
- (1)
- (2)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (3)
- (2)
- (1)
- (1)
- (4)
- (2)
- (2)
- (1)
- (4)
- (2)
- (3)
- (22)
- (7)
- (2)
- (4)
- (5)
- (2)
- (3)
- (26)
- (1)
- (177)
- (9)
- (17)
- (39)
- (70)
- (52)
- (9)
- (15)
- (2)
- (2)
- (8)
- (10)
- (1)
- (5)
- (2)
- (4)
- (19)
- (2)
- (7)
- (2)
- (4)
- (6)
- (5)
- (2)
- (3)
- (3)
- (11)
- (3)
- (63)
- (16)
- (166)
- (2)
- (1)
- (124)
- (5)
- (42)
- (2)
- (2)
- (3)
- (494)
- (2)
- (5)
- (3)
- (5)
- (3)
- (4)
- (2)
- (2)
- (2)
- (31)
- (1)
- (66)
- (6)
- (3)
- (81)
- (2)
- (1)
- (2)
- (1)
- (2)
- (1)
- (2)
- (1)
- (1)
- (3)
- (1)
- (2)
- (1)
- (1)
- (1)
- (3)
- (2)
- (2)
- (4)
- (3)
- (1)
- (2)
- (5)
- (3)
- (1)
- (2)
- (2)
- (2)
- (3)
- (1)
- (1)
- (2)
- (1)
- (2)
- (1)
- (4)
- (1)
- (1)
- (2)
- (1)
- (1)
- (2)
- (1)
- (2)
- (2)
- (1)
- (3)
- (2)
- (2)
- (1)
- (4)
- (2)
- (2)
- (1)
- (3)
- (2)
- (2)
- (2)
- (1)
- (3)
- (3)
- (5)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
Filtered Search Results
Medchemexpress LLC Farudodstat (ASLAN003) | 1035688-66-4 | 99.7% | 100 MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Farudodstat (ASLAN003) is an orally active and potent Dihydroorotate Dehydrogenase (DHODH) inhibitor with an IC50 of 35 nM for the human DHODH enzyme. Its mechanism of action involves inhibiting protein synthesis by activating AP-1 transcription factors. This compound induces apoptosis and significantly prolongs survival in acute myeloid leukemia (AML) xenograft mice.
- Exhibits antiproliferative activity against various human cell lines.
- Inhibits leukemic cell proliferation in vitro.
- Increases cleaved caspase 8.
- Decreases viability and induces differentiation in primary acute myeloid leukemia blasts and myelodysplastic syndrome samples.
- Inhibits protein synthesis by reducing O-propargyl-puromycin (OPP) incorporation and downregulating EIF4B and RPL6 proteins.
- Substantially reduces the number and size of disseminated tumors in vivo.
- Available as a white to off-white solid.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
eMolecules 890839-66-4 | 8-(Trifluoromethyl)chroman-4-one | ChemScene | MFCD11506686 | 216.159 | C10H7F3O2 | 97.000 | FC(F)(F)c1cccc2C(=O)CCOc12 | 100mg | 572175906
8-(Trifluoromethyl)chroman-4-one | ChemScene | 890839-66-4 | MFCD11506686 | 216.159 | C10H7F3O2 | 97.000 | FC(F)(F)c1cccc2C(=O)CCOc12 | 100mg | 572175906
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Medchemexpress LLC Dicentrine | 517-66-8 | 5 MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Dicentrine is a natural product isolated from the plant Stephania epigaea Lo that exhibits an antihypertensive effect. It functions as an α1-adrenoceptor antagonist and has been shown to be effective against human hyperplastic prostates.
- Isolated from the plant Stephania epigaea Lo.
- Exhibits an antihypertensive effect.
- Functions as an α1-adrenoceptor antagonist.
- Effective against human hyperplastic prostates.
- For research use only.
- High purity (99.94%).
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Medchemexpress LLC TAO Kinase inhibitor 1 | 850467-66-2 | 99.8% | 384.47 | 100 MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
TAO Kinase inhibitor 1 (compound 43) is a selective, ATP-competitive thousand-and-one amino acid kinases (TAOK) inhibitor with IC50s of 11 to 15 nM for TAOK1 and 2. It delays mitosis and induces mitotic cell death. It is for research use only.
- Selective, ATP-competitive TAOK inhibitor.
- IC50s of 11 to 15 nM for TAOK1 and 2.
- Delays mitosis.
- Induces mitotic cell death.
- Purity: 99.81%.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Chem-Impex International, Inc. 2-(2-Methyl-1H-indol-3-yl)ethylamine | 2731-06-8 | MFCD00130185 | 1G
2-(2-Methyl-1H-indol-3-yl)ethylamine, 2731-06-8, MFCD00130185, 1G
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Medchemexpress LLC DX3-213B | 2749555-66-4 | 99.7% | C20H28F2N2O5S2 | 100 MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
DX3-213B is a highly potent, orally active oxidative phosphorylation (OXPHOS) complex I inhibitor with an IC50 of 3.6 nM. It effectively impairs ATP generation with an IC50 of 11 nM and blocks the growth of MIA PaCa-2 cells, also with a GI50 of 11 nM. This compound is utilized in research concerning pancreatic cancer.
- Highly potent and orally active.
- Functions as an oxidative phosphorylation (OXPHOS) complex I inhibitor.
- Impairs ATP generation.
- Blocks MIA PaCa-2 cell growth.
- Used in pancreatic cancer research.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
eMolecules 155877-83-1 | Medchem Express | LE135 | 5mg | 596366425 | HY-107436 | MFCD06798318 | 438.571 | C29H30N2O2
Ambeed | (S)-tert-Butyl 2-aminopropanoate | 1g | 572830027 | A605887 | 21691-50-9 | MFCD00270591 | 145.202 | C7H15NO2
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link:
eMolecules Building Block Tool<|a>
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
![eMolecules 370882-66-9 | tert-butyl (1S,5R)-3,6-diazabicyclo[3.2.0]heptane-6-carboxylate | Pharmablock198.266 | C10H18N2O2 | 97.000 | CC(C)(C)OC(=O)N1C[C@@H]2CNC[C@H]12 | 25mg | 586144518](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502457612.PNG-250.jpg)
eMolecules 370882-66-9 | tert-butyl (1S,5R)-3,6-diazabicyclo[3.2.0]heptane-6-carboxylate | Pharmablock198.266 | C10H18N2O2 | 97.000 | CC(C)(C)OC(=O)N1C[C@@H]2CNC[C@H]12 | 25mg | 586144518
tert-butyl (1S,5R)-3,6-diazabicyclo[3.2.0]heptane-6-carboxylate | Pharmablock | 370882-66-9198.266 | C10H18N2O2 | 97.000 | CC(C)(C)OC(=O)N1C[C@@H]2CNC[C@H]12 | 25mg | 586144518
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Medchemexpress LLC Nevadensin | 10176-66-6 | MFCD08689947 | 344.32 | 20 MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Nevadensin is a natural flavonoid and a selective human carboxylesterase 1 (hCE1) inhibitor. It demonstrates greater selectivity for hCE1 over hCE2.
- Induces apoptosis and DNA damage in cancer cells.
- Possesses anti-inflammatory, anti-tumor, anti-hypertensive, anti-tubercular, antitussive, antioxidant, and anti-microbial activities.
- Inhibits hCE1 with an IC50 of 2.64 μM.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Medchemexpress LLC SIRT-IN-2 | 1431411-66-3 | 98.1% | 383.49 | 50 MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
SIRT-IN-2 is a potent inhibitor of SIRT1/2/3, with IC50s of 4, 4, 7 nM, respectively. It is described as one of the most potent truncated pan SIRT1/2/3 inhibitors. SIRT-IN-2 (compound 31) binds identically in the catalytic active site (RMS=0.29), occupying the nicotinamide C-pocket and acetyl lysine substrate channel.
- Potent inhibitor of SIRT1/2/3
- IC50s of 4, 4, 7 nM for SIRT1, SIRT2, and SIRT3
- Truncated pan SIRT1/2/3 inhibitor
- Binds in the catalytic active site
- Occupies nicotinamide C-pocket and acetyl lysine substrate channel
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Medchemexpress LLC Dx3-213b | 2749555-66-4 | 99.7% | 478.57 g/mol | C20H28F2N2O5S2 | 5 MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
DX3-213B is a potent, orally active oxidative phosphorylation (OXPHOS) complex I inhibitor used in preclinical research. It disrupts mitochondrial ATP production and exhibits cellular activity in cancer models, making it useful for mechanistic studies of mitochondrial function and cancer metabolism. Not for human use.
- Highly potent complex I inhibition (IC50 = 3.6 nM)
- Impairs ATP generation in cells (IC50 = 11 nM)
- Inhibits growth of pancreatic cancer cell line (GI50 = 11 nM)
- High chemical purity suitable for biochemical assays
- Available as solid and DMSO solution for assay flexibility
- Intended for mechanistic mitochondrial and cancer metabolism research
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
eMolecules 181144-66-1 | Medchem Express | Co 102862 | 5mg | 722714018 | HY-108504 | MFCD00953614 | 273.267 | C14H12FN3O2
Medchem Express | NRX-1933 | 5mg | 713706709 | HY-144984 | 2763260-30-4 | 350.261 | C14H9F3N6O2
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link:
eMolecules Building Block Tool<|a>
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
eMolecules 1214387-66-2 | 3-METHYL-4-(TRIFLUOROMETHYL)BENZOIC ACID ETHYL ESTER | AstaTech | MFCD14698275 | 232.202 | C11H11F3O2 | 95.000 | CCOC(=O)c1ccc(c(C)c1)C(F)(F)F | 1g | 296384189
3-METHYL-4-(TRIFLUOROMETHYL)BENZOIC ACID ETHYL ESTER | AstaTech | 1214387-66-2 | MFCD14698275 | 232.202 | C11H11F3O2 | 95.000 | CCOC(=O)c1ccc(c(C)c1)C(F)(F)F | 1g | 296384189
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
eMolecules 74290-66-7 | 2-Amino-3,5-dibromo-6-methylpyrazine | ChemScene | MFCD08705764 | 266.924 | C5H5Br2N3 | 98.000 | Cc1nc(N)c(Br)nc1Br | 100mg | 801476141
2-Amino-3,5-dibromo-6-methylpyrazine | ChemScene | 74290-66-7 | MFCD08705764 | 266.924 | C5H5Br2N3 | 98.000 | Cc1nc(N)c(Br)nc1Br | 100mg | 801476141
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Medchemexpress LLC PGAM1-IN-2 | 2438637-66-0 | 98.0% | 10 MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
PGAM1-IN-2 is a phosphoglycerate mutase 1 (PGAM1) inhibitor with an IC50 of 2.1 μM. This compound inhibits H1299 proliferation with an IC50 of 33.8±6.1 μM.
- Potent phosphoglycerate mutase 1 inhibitor
- Inhibits H1299 proliferation
- Suitable for research applications
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More